Fondaparinux Sodium for The Preparation of Finished Drugs

• Customization: Available
• Function: Antineoplastic, Immune System Drugs, Diagnostic Agents, Anesthetic and Adjuvant, Nervous System Drugs, Visceral System Medication, Central Nervous System Agents, Cardiovascular Agents, Respiratory System Agents, Disinfectant and Preservatives
• Certification: GMP
• Model NO.: Customized on demand
• Grade Standard: Medicine Grade
• Type: Chemical Reagent
• State: Solid
• Volatile: Not Volatile
• Storage Conditions: Store Away From Light
• Transport Package: According to Customer Requirements
• Specification: Customized on demand
• Trademark: none
• Origin: China

Product Description

decasodium (2R,3S,4S,5R,6R)-3-[(2R,3R,4R,6R)-5-[(2R,3R,4S,5S,6S)-6-carboxylato-5-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-3-(sulfonatoamino)-6-(sulfonatooxymethyl)oxan-2-yl]oxy-3,4-dihydroxy-oxan-2-yl]oxy-3-(sulfonatoamino)-4-sulfonatooxy-6-(sulfonatooxymethyl)oxan-2-yl]oxy-4-hydroxy-6-[(2R,3S,4R,5R,6S)-4-hydroxy-6-methoxy-5-(sulfonatoamino)-2-(sulfonatooxymethyl)oxan-3-yl]oxy-5-sulfonatooxy-oxane-2-carboxylate;
The risk of bleeding may be increased when this product is used in combination with drugs that increase the risk of bleeding. Oral anticoagulants (warfarin), platelet inhibitors (acetylsalicylic acid), non-steroidal anti-inflammatory drugs (piroxicam), and digoxin did not affect the pharmacokinetics of this product. The dose of this product (10 mg) used in the drug interaction study was higher than the recommended dose used for the indication of this product. This product neither affects the activity of warfarin INR, nor the bleeding time during treatment with acetylsalicylic acid or piroxicam, nor the pharmacokinetics of digoxin at steady state.
Subsequent treatment with another anticoagulant drug: If subsequent treatment will be with heparin or low molecular weight heparin, the first injection should usually be given 1 day after the last injection. If subsequent therapy with a vitamin K antagonist is required, therapy with fondaparinux should be continued until the target INR is reached.